An important factor wearing and stretching the chain is the angle and the number of rotations at each rivet. The actual force pulling it doesn't do much, as long as the parts don't move in relation to each other. I found that the killer for the chain is cutting a great number of small diameter limbs, like shredding them in the trailer/truck to make room for more. I saw a brand new chain on a 200T becoming unusable in just one day doing that. The slack went out of range of the adjuster. The chain folds / unfolds at both ends, but oscillates too in a wave form in between. Plus, the cutting links tend to rock back and forth each time they encounter and exist the wood. The more slack in the system, the more movements you get at the rivets of course. On the other side, over tightening the chain may reduce the oscillations, but that tends to squeeze the oil out of the tiny contact surfaces between the rivets and the links. Heavy load and poor lubrication, you guess easily the result.
The steel's properties are important too, Oregon's needs a more frequent tightening than Stihl's.
To me, "tightening" is a very bad word to name the process, like if you had to torque down a bolt. I'd prefer to use "adjusting", because if the slack needs indeed to be removed, the chain prefers to stand barely any tension in it.
To do that, i first pull up hard on the chain to get all the rivets in their working position (useful for the chain coming from the tool box), then I let go the chain to collect the slack on the bottom. I lift the bar's nose and turn the adjusting screw to remove the slack until the chain makes juuust contact with the underside of the bar, just a light kiss. If it's an hard nose bar like on the 44", I live it a little less close to get less friction on the nose. Still holding the nose up, I tighten the bar's nuts (real term this time). Then I verify it by spinning the chain by hand. It should go smoothly. Sometimes, I have to back up a little to free it a bit, mostly with the ms150T, as tightening the nut on this one tends curiously to tighten the chain too.