He doesn't cover the subject at great length, the picture I mentioned earlier speaks volumes. It shows the from the pith to about 50% of the xylem is discolored. The injection sites are seen like teeth on a sprocket to the outside of the necrotic xylem.
The micro injection course I took stated we had to keep a steady stream of water on the drill hole until we had the needle (pressurized vessel) installed. The cambium initiates CODIT to start that fast! Air is the key.
Another study states this:
The final blow out circumstance involves
premature withdrawal of the injector head before
all the material has been expelled into the tree.
The material under pressure that has not yet been
taken up may "bleed" back to the outside of the
hole as the head is removed. This may result in
cambial dieback adjacent to the hole and in trunk
discoloration. This is not to be confused with
weeping that can occur for a long period after injector
head removal.
Bark splitting is the end result of cambial
dieback resulting in a trunk canker. In this case,
there is a bark rupture in a vertical plane up and
down from the point of injection or blow out. There
has also been speculation that the injection hole
itself becomes a focal point (locus) for frost
cracks or fulcrum point for future frost cracks if
the injection hole has been plugged.
Dr. Shigo states in his book "A New Tree Biology" that holes should be shallow and smaller than 8mm in diameter. the caption under the picture I mentioned states "Treatments that cause serious internal injuries must be stopped. (A single injection treatment with a growth regulator.)"